Non Clinical Applications

Preclinical:

Microwave radiation from animals allows to get a fundamentally  new information about the processes of metabolism,  perfusion (microcirculation) and cellular kinetics in malignancies.

micertm

Protein denaturation kinetics:

Process of denaturation can be monitored using microwaves. This method does not require any isotopes or fluorescent labels. It is simple and low cost in comparison with calorimeters and optical spectrometers and provides new opportunities in the study of protein denaturation with additional allowance for quantum effects associated with the ratio of ortho/para isomers of water.

 

albumin

Enzyme CYP102 A1:

It was found that in the process of hydroxylation of heme-containing enzyme CYP102 A1, the radiation generation of microwave range can be observed. The discovered effect can be used in enzyme systems studies, particularly as it is associated with the appearance of the interaction of the enzyme system with a fine structure of the microenvironment (which is a non-equilibrium liquid in terms of the ratio of ortho and para isomers of water), resulting in a change of state of this liquid. Thus, the study of this phenomenon is important to clarify the mechanism of interaction of the functioning enzyme system with the microenvironment.

 

cyp102

Horse radish peroxidase:

Microwave emission form the solution of functioning horse radish peroxidase (HRP) and containing luminol in the 3.4-4.2 GHz range has been registered. In the passive-mode measurements, microwave emission with corresponding increase in TSHF by 0.5 °C was observed. The influence of the pulsed electric field on the microwave emission from the HRP solution has been investigated. It has been shown that the increase in the level of microwave emission from the solution in the presence of pulsed electric field was much greater, up to 2 °C.

 

peroxidase

 


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